| The Harrison-Hill Collation........ |
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| Tracey
at Work
Griffith
University! Sometimes I feel as if it should be my home rather than
a workplace. I've worked at Griffith as an associate lecturer since 1992.
I completed my undergraduate degrees there, and I even lived on campus
for five years, so in some weird illogical way it seems somewhat like
home. Scary Thought Though!!! In 2000
I also completed a Graduate Diploma in Higher Education. The aim of this
course was to update my knowledge about effective teaching methods in
the higher education sector with a focus on promoting a quality learning
environment. With the communication millennium here, I am especially interested
in flexible learning in its many shapes and forms.
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| Glenn
at Work
As already mentioned, I am a cardiac scientist by trade which broadly means I do heart research for a living. I am based at the Heart Foundation Research Centre within the School of Health Science at Griffith University Gold Coast. We have approximately 10-12 people working in the centre ranging from senior investigators through post-docs to Ph.D / Honours and Research Assistants and students. Our laboratory is supported by the National Heart Foundation and through competitive grants. Heart disease is a bit like cancer, we will probably never cure it but we continue to do research which helps understand the causes and gives us ideas for treatments and how to better manage patients with heart problems. Heart disease is responsible for nearly 1/3 of all deaths in the industrialized world, as many as cancer and it costs our government many millions to treat heart patients, (they don't give much to heart research unfortunately, not to whinge of course). As you know the heart is an amazing organ, it is the only organ which does substantial work every minute of day, in fact it beats 100000 times a day and pumps 90000 litres of blood per 24 hours. If you would like to know more facts about your heart, how it works, what happens in heart disease as well as information of diets and healthy heart living have a look at the Australian Heart Foundation at or the American Heart Association site.
- the role of oxygen free radicals in heart during and after a heart attack - the effects of aging on the heart - understanding the genetic signals that make heart tissue unique, it is one of the only tissues which cannot repair itself after damage is done which is why so many people die from heart attacks - we study the role of adenosine in improving the pumping efficiency of the heart during exercise and after a heart attack - how the heart produces and regulates its energy supply and own blood flow is also of great interest to us. As you can see we are looking at a lot of problems, we do not produce heart drugs as such but often test new compounds in our preparations to see their potential. Much of our research is focussing on the compound ADENOSINE, it is a naturally occuring substance in the heart and it has a lot of beneficial effects like dilating blood vessels to maximise flow, slowing the heart rate, improving the hearts use of oxygen, enhancing the pumping force of the heart. We have shown it is important during exercise and after coronary occulsion to maximise recovery of heart function. Unfortunately it does not last long in the blood so we cannot give it to heart patients but the drug design people are working on that problem.
That is enough about my
work, any questions you have please email
me and I would be happy to answer them or put you in touch with those
who could. If you would like to read my CV and the papers I have published
during my research so far you can view it below….. |
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Harrison GJ, van Wihje MH, de Groot B, Dijk FJ, van Beek JHGM. (1999) Creatine kinase inhibition accelerates transcytosolic energy signaling during rapid work load steps in isolated rabbit hearts. American Journal of Physiology 276 (1):H134-H140. Rose'Meyer RB, Harden FA, Varela JI, Harrison GJ, Willis RJ (1999) Age-related changes to adenosine in rat coronary resistance vessels. General Pharmacology 32:35-40. Harrison GJ, Willis RJ, Headrick JP (1998) Extracellular adenosine levels and cellular energy metabolism in ischemically preconditioned rat heart. Cardiovascular Research 40(1):74-87. Harrison GJ, Harden FA, Jordan LR, Varela JI, Willis RJ (1996) A method to evaluate the response of the coronary circulation of perfused rat heart to adenosine. Canadian Journal of Physiology and Pharmacology 74(2):145-149. Harden FA, Harrison GJ, Headrick JP, Jordan LR, Willis RJ (1996) A biphasic response to adenosine in the coronary vasculature of the potassium-arrested perfused rat heart. European Journal of Pharmacology 307(1):49-53. Harrison GJ, Jordan LR, Selley ML, Willis RJ (1995) Low-density lipoproteins inhibit histamine and NaNO2 relaxations of the coronary vasculature and reduce contractile function in isolated rat hearts. Heart and Vessels 10(5): 249-257. Harrison GJ, Jordan LR, Willis RJ (1994) Deleterious effects of hydrogen peroxide on the function and ultrastructure of cardiac muscle and the coronary vasculature of perfused rat hearts. Canadian Journal of Cardiology 10(8): 843-849. |
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Page Last updated on 10
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